No Highway in the Sky (1951), directed by Henry Koster.
A scientist predicts catastrophic failure of a new alloy (via cold fission!) used in an airliner, and then finds himself over the Atlantic in just such a plane as it approaches its final hour. Crazy as he sounds, the captain and crew begin to believe him, and it becomes a white-knuckle flight. And that's just the first half.
Fondly remembered and just recently available on DVD-R, this is an early example of the airplane disaster film genre that would become popular many years later. It's good as a psychological portrait of the lone man courageously doing outlandish things that he feels to be right.
James Stewart is fine as the absent minded professor, and he appears again -- after Destry Rides Again (1939) -- with Marlene Dietrich, quite good as a humane film star trapped with him on the flight.
Many other well-known British cinema faces. The daughter is Janette Scott, age 13.
A nice subplot: it is the story of a man, damaged by the loss of his wife in the war, who regains his humanity after hiding in the cold, emotionless world of mathematics and engineering.
Like all DVD-R titles of a certain age, it's available for rent from ClassicFlix. [Later: Kino has the Blu-ray].